Serum biomarker linked to brain atrophy in multiple sclerosis

(HealthDay)—Serum neurofilament light chain (sNFL) levels are significantly associated with clinical and neuroimaging outcomes in multiple sclerosis (MS), according to a study published online Aug. 12 in JAMA Neurology. Ester Cantó, Ph.D., from the University of California in San Francisco, and colleagues conducted a prospective cohort study involving 607 patients Continue Reading

Dynamic reorganization of brain circuit with post-stroke rehabilitation

Nagoya City University (NCU) researchers have revealed an interaction between cortico-brainstem pathways during training-induced recovery in stroke model rats, providing valuable insights for improving rehabilitation methods. Upper limb hemiparesis often occurs after ischemic or hemorrhagic stroke. Unilateral upper extremity impairment can substantially disturb patients’ ability to complete activities of daily Continue Reading

Slowing brain rhythms can serve as a marker for delirium and its clinical outcomes

An EEG (electroencephalogram) can provide a valuable biomarker for detecting delirium, a serious mental disturbance that is often underrecognized, as well as predicting poor clinical outcomes, researchers from Massachusetts General Hospital (MGH) have found. In a paper published in Neurology, the team reported that the generalized slowing of brain rhythms, Continue Reading

Brain cells that suppress drug cravings may be the secret to better addiction medicines

For the nearly 20 million U.S. adults who are addicted to drugs or alcohol, no effective medical treatment exists—despite plentiful scientific knowledge surrounding the factors that trigger relapse. It’s a quandary that prompted a research quest for Nobuyoshi Suto, Ph.D., of Scripps Research’s Department of Neuroscience. Rather than continue to Continue Reading

‘Superagers’ over 80 have the memory and brain connectivity of twenty-somethings

Research published in the journal Cerebral Cortex has shown that stronger functional connectivity—that is, communication among neurons in various networks of the brain—is linked to youthful memory in older adults. Those with superior memories—called superagers—have the strongest connectivity. The work is the second in a series of three studies undertaken Continue Reading