Comparison of three similar frontline breast cancer drugs reveals important differences

Every year, more than 250,000 women in the U.S. are diagnosed with breast cancer. When detected early, patients with the most common form鈥攚hich tests positive for hormone receptors (HR+) and negative for the HER2 receptor鈥攗sually respond well to treatment. But for those in advanced stages, few treatment options existed until Continue Reading

Researchers develop method for identifying aggressive breast cancer drivers

Precision cancer medicine requires personalized biomarkers to identify patients who will benefit from specific cancer therapies. In an effort to improve the accuracy of predictions about prognosis for patients with breast cancer and the efficacy of personalized therapy, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a Continue Reading

BAFfling cancer growth strategies: New targets for chromatin remodeling mutations identified

More than one-fifth of all human cancers harbor mutations in one of the members of the BAF chromatin remodeling complex. Deep biochemical and epigenomic characterization of a cell line panel comprehensively representing all these mutations enabled researchers at the CeMM Research Center for Molecule Medicine of the Austrian Academy of Continue Reading

Could microorganisms in poop help treat the deadliest form of skin cancer?

A multidisciplinary team at Lawson Health Research Institute is exploring whether fecal transplants can improve outcomes in melanoma patients treated with immunotherapy. Immunotherapy drugs stimulate a person’s immune system to attack and destroy cancer. While they can significantly improve survival outcomes in those with melanoma, they are only effective in Continue Reading

Exercise associated with benefit to patients with advanced colorectal cancer

Patients with metastatic colorectal cancer who engaged in moderate exercise while undergoing chemotherapy tended to have delayed progression of their disease and fewer severe side effects from treatment, according to the results of a new study. Even low-intensity exercise, such as walking four or more hours a week, was associated Continue Reading