Scientists discover hidden differences among cells that may help them evade drug therapy

University of Maryland researchers have discovered that seemingly identical cells can use different protein molecules to carry out the same function in an important cellular process. The scientists named this newly discovered variability “functional mosaicism,” and it has significant implications for the development of therapeutic treatments, which are often designed Continue Reading

Researcher studies differences in the immune systems of men and women

Females are less susceptible to infection but are 10 times more likely than males to develop an autoimmune disorder, such as hypothyroidism or rheumatoid arthritis. The female immune system is “a double-edged sword” in that way, said Jennifer Franko, a teaching assistant professor in the Department of Microbiology, Immunology and Continue Reading

Genes responsible for sex-related differences in cancer aggressiveness found in vinegar flies

An understanding of the molecular basis of differences in the incidence and survival of cancer between men and women may allow the discovery of specific and more effective treatments. The study, published in Science Advances, compares the brain tumors of male and female flies at the molecular level and identifies Continue Reading

Children with ADHD have differences in part of brain controlling movement

(HealthDay)—Children with attention-deficit/hyperactivity disorder (ADHD) may have differences in the brain that limit appropriate responses to “stop cues,” according to a study published online July 17 in Neurology. Donald L. Gilbert, M.D., from the University of Cincinnati, and colleagues evaluated resting motor cortex (M1) physiology during a cognitive control task Continue Reading

Study identifies genetic differences that may increase risk of obesity, diabetes

In a Finnish study that included researchers from UCLA, the DNA from nearly 20,000 people was harnessed to identify genetic mutations that may increase the risk of diabetes, high cholesterol and other diseases and conditions. The findings, published in the journal Nature, suggest the potential for using genomic sequencing to Continue Reading

More biological differences discovered: Pain originates differently in males than in females

According to the results of a study by researchers from The University of Texas at Dallas, at the cellular level, “pain begins differently for men and women.” The group of researchers, which included Dr. Ted Price, Dr. Salim Megat, and their colleagues in the Pain Neurobiology Research Group, has determined that handling receptors Continue Reading