Low vitamin D levels linked to non-motor symptoms in patients with Parkinson’s disease

In an Acta Neurologica Scandinavia study of 182 patients with Parkinson’s disease and 185 healthy controls, patients with Parkinson’s disease had significantly lower levels of vitamin D in their blood. Also, patients with lower vitamin D levels were more likely to fall, and to experience sleep problems, depression, and anxiety. Continue Reading

Prenatal parental stress linked to behaviour problems in toddlers

Expectant parents’ emotional struggles predict emotional and behavioural problems in 2-year-olds, new research shows. The same study reveals, for the first time, that couple conflict helps explain emotional problems in very young children. The team of researchers—from the Universities of Cambridge, Birmingham, New York and Leiden—say their findings highlight a Continue Reading

Psoriasis therapy linked to reduced coronary inflammation in patients with skin condition

Researchers have found that anti-inflammatory biologic therapies used to treat moderate to severe psoriasis can significantly reduce coronary inflammation in patients with the chronic skin condition. Scientists said the findings are particularly notable because of the use of a novel imaging biomarker, the perivascular fat attenuation index (FAI), that was Continue Reading

SGLT-2 inhibitor use not linked to increased risk for UTI events

(HealthDay)—Initiation of therapy with sodium-glucose cotransporter-2 (SGLT-2) inhibitors for type 2 diabetes mellitus is not associated with an increased risk for urinary tract infection (UTI) events compared with initiation of other second-line antidiabetic medications, according to a study published online July 30 in the Annals of Internal Medicine. Chintan V. Continue Reading

Brain region linked to altered social interactions in autism model

Although psychiatric disorders can be linked to particular genes, the brain regions and mechanisms underlying particular disorders are not well-understood. Mutations or deletions of the SHANK3 gene are strongly associated with autism spectrum disorder (ASD) and a related rare disorder called Phelan-McDermid syndrome. Mice with SHANK3 mutations also display some Continue Reading