Genetically manipulating protein level in colon cancer cells can improve chemotherapy

Colorectal cancer outcomes may improve by genetically altering an immune-regulatory protein in cancer cells, making the cells more vulnerable to chemotherapy. That’s according to new Mayo Clinic research. The findings, published this month in Oncogene, indicate that increasing the expression of the PD-L1 protein in colorectal cancer cells can improve Continue Reading

Manipulating dose, timing of two therapies reduces relapse in mouse models of breast cancer

Changing the standard dose and timing of two therapies greatly cut tumor relapse and reduced side effects in mouse models of kinase mutated breast cancer and lung cancer, UT Southwestern Simmons Cancer Center researchers have found. The study published today in Science Immunology suggests that giving the two therapies as Continue Reading