Researchers develop method for identifying aggressive breast cancer drivers

Precision cancer medicine requires personalized biomarkers to identify patients who will benefit from specific cancer therapies. In an effort to improve the accuracy of predictions about prognosis for patients with breast cancer and the efficacy of personalized therapy, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a Continue Reading

New diagnostic method for fungal infections could combat a major global health risk

A new study from The Westmead Institute for Medical Research (WIMR) has demonstrated how dual DNA barcoding could help improve the diagnosis of invasive fungal diseases, giving patients access to potentially life-saving treatment much sooner. The early detection of fungal pathogens—the specific species of fungi responsible for disease—is crucial in Continue Reading

Method to calculate central line infections flawed

(HealthDay)—Using the true number of central lines as the denominator improves methods of determining central line-associated bloodstream infection (CLABSI) rates, according to a study published online July 24 in Infection Control & Hospital Epidemiology. Jesse Couk, M.D., from Emory University in Atlanta, and colleagues compared CLABSI rates using standard National Continue Reading

A new method of tooth repair? Scientists uncover mechanisms to inform future treatment

Stem cells hold the key to wound healing, as they develop into specialised cell types throughout the body—including in teeth. Now an international team of researchers has found a mechanism that could offer a potential novel solution to tooth repair. Published today (Friday 9 August) in Nature Communications, the study Continue Reading

Researchers study new method of assessing severity of children’s brain injuries

A team of international scientists, including Melbourne researchers, has found blood samples can help gauge the severity of children’s brain injuries, indicating which children will recover and which will need ongoing support. The Murdoch Children’s Research Institute (MCRI), working with Canadian scientists, analysed blood from 158 children who presented with Continue Reading

New method helping to find deletions and duplications in the human genome

A new machine-learning method accurately identifies regions of the human genome that have been duplicated or deleted—known as copy number variants—that are often associated with autism and other neurodevelopmental disorders. The new method, developed by researchers at Penn State, integrates data from several algorithms that attempt to identify copy number Continue Reading

New method helping to find deletions and duplications in the human genome

A random-forest, machine-learning method for identifying copy number variation from exome-sequencing data. A forest of hundreds of decision trees is trained on a validated set of genetic deletions and duplication, the model built from these trees can then be used to accurately identify copy number variation in sample exome-sequencing data. Continue Reading

Animal organ HARVESTING farms coming soon? Researchers develop method to “refurbish” harvested animal organs for human transplant

There is an organ-transplant crisis going on. There are far too many people on various organ transplant waiting lists, and not enough organ donors. As such, scientists have thought of various solutions for the problem. One new example is organ refurbishing, which is as straightforward as it sounds – scientists Continue Reading

Method review for increasing consumption of vegetables in early childhood

A review of studies published in the journal Current Nutrition Reports looked at the possible methods for increasing vegetable consumption in early childhood, and offered advice for practitioners. Researchers reviewed studies that used different methods to increase vegetable consumption in children aged two to five years. They used the key Continue Reading

Scientists discover breakthrough method for engineering gut bacteria to treat certain health conditions

Even though many people associate bacteria with illness, they actually have a symbiotic relationship with humans wherein they help us and we help them. In fact, the gastrointestinal tract is almost like an auxiliary central nervous system, “talking” to other parts of the body using a chemical language that is Continue Reading