Researchers identify key areas of measles virus polymerase to target for antiviral drug development

Targeting specific areas of the measles virus polymerase, a protein complex that copies the viral genome, can effectively fight the measles virus and be used as an approach to developing new antiviral drugs to treat the serious infectious disease, according to a study by the Institute for Biomedical Sciences at Continue Reading

Researchers discover that fasting reduces inflammation and improves chronic inflammatory diseases

Fasting regimens have gained public and scientific interest in recent years, but fasting shouldn’t be dismissed as a fad. In a study published in Cell, Mount Sinai researchers found that fasting reduces inflammation and improves chronic inflammatory diseases without affecting the immune system’s response to acute infections. While acute inflammation Continue Reading

Researchers use single-cell sequencing to get a better look at human embryo implantation

A team of researchers affiliated with multiple institutions in China has used single-cell sequencing to learn more about the human embryo during implantation in the uterus. In their paper published in the journal Nature, the group describes sequencing thousands of human embryo cells from before, during and after implantation, and Continue Reading

Researchers develop method for identifying aggressive breast cancer drivers

Precision cancer medicine requires personalized biomarkers to identify patients who will benefit from specific cancer therapies. In an effort to improve the accuracy of predictions about prognosis for patients with breast cancer and the efficacy of personalized therapy, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a Continue Reading

Researchers identify protein governing platinum resistant ovarian cancer

The extracellular regulated kinase (ERK) protein is an important mechanism behind platinum-resistance in platinum-resistant ovarian cancer, according to a study from a research team at the George Washington University (GW) Cancer Center. The study, which is the first to provide clinical evidence confirming a link between ERK and hypoxia-inducible factor Continue Reading

Researchers show how probiotics benefit vaginal health

Researchers have shown that three genes from a probiotic Lactobacillus species, used in some commercial probiotic vaginal capsules, are almost certainly involved in mediating adhesion to the vaginal epithelium. This is likely critical to how this species benefits vaginal health. “These results could help us screen for better probiotic candidates Continue Reading