Encapsulated Indian medicinal herb shows anti-diabetic properties in mice

Extracts of the herb Withania coagulans, or Paneer dodi, are used in traditional Indian medicine. Although some healers claim that W. coagulans can help treat diabetes, the bitter-tasting plant hasn’t been studied extensively by scientists. Now, researchers have found that herbal extracts packaged in polymers derived from natural substances can Continue Reading

Enzalutamide shows survival benefit in men with metastatic prostate cancer

A combination of enzalutamide and androgen deprivation therapy (ADT) significantly reduced the risk of metastatic progression or death over time in men with advanced prostate cancer, according to the results of clinical trial led by Duke Cancer Institute. The findings, published in the Journal of Clinical Oncology, were the product Continue Reading

Study shows stimulation of the ear can help manage Parkinson’s symptoms

A new study led by the University has shown that gentle, controlled stimulation of the ear canal can help reduce symptoms of Parkinson’s disease. The randomized, controlled study showed that twice-daily stimulation for two months was associated with a significant reduction in both motor and non-motor features of Parkinson’s disease. Continue Reading

New evidence shows cytotoxic T cells can identify, invade, and destroy targets of large mass like T. gondii tissue cysts

CD8+ cytotoxic T lymphocytes can kill host cells infected with various microorganisms as well as single individual cancer cells through direct cell-to-cell contact, but their ability to destroy a target of large mass remains unexplored. A study in The American Journal of Pathology provided novel evidence on the capability of Continue Reading

New analysis shows drug slows down respiratory decline

Duchenne muscular dystrophy occurs in boys and is characterized by progressive muscle degeneration and weakness leading to a decline in respiratory function. Strategies to arrest this severe progressive deterioration are needed to extend lives and improve quality of life. Results of three clinical trials using eteplirsen, an exon-skipping antisense oligonucleotide, Continue Reading

New evidence shows cytotoxic T cells can identify, invade, and destroy targets of large mass like T. gondii tissue cysts

Three-dimensional images of T. gondii cysts containing CD8+ T cells that had fully invaded into the cysts detected in the brains of infected nude mice that received a transfer of CD8+ immune T cells. Sections (4 um thick) of their brains were applied for immunohistochemical staining for T. gondii (brown) Continue Reading