Combinatorial therapy shows early promise in patients with relapsed small cell lung cancer

The PARP inhibitor olaparib (Lynparza) in combination with the chemotherapeutic agent temozolomide (Temodar) showed clinical efficacy in patients with relapsed small cell lung cancer (SCLC), according to results from a phase I/II clinical trial published in Cancer Discovery, a journal of the American Association for Cancer Research. “Small cell lung Continue Reading

Study shows pediatricians can help parents to quit smoking

An NIH-funded study published in JAMA Pediatrics has shown pediatricians can help parents quit smoking. The research, led by investigators at Massachusetts General Hospital for Children (MGHfC), was conducted across five states—North Carolina, Tennessee, Virginia, Ohio and Indiana—and delivered a simple, customizable intervention: Upon check-in at their child’s appointment, parents Continue Reading

MSI detection via liquid biopsy shows high concordance with results from tissue samples

Bottom Line: Incorporation of pan-cancer microsatellite instability (MSI) detection into the 74-gene panel Guardant360 liquid biopsy assay showed high concordance with matched tissue samples in nearly 1,000 patients. Journal in Which the Study was Published: Clinical Cancer Research, a journal of the American Association for Cancer Research Authors: Martina Lefterova, Continue Reading

Encapsulated Indian medicinal herb shows anti-diabetic properties in mice

Extracts of the herb Withania coagulans, or Paneer dodi, are used in traditional Indian medicine. Although some healers claim that W. coagulans can help treat diabetes, the bitter-tasting plant hasn’t been studied extensively by scientists. Now, researchers have found that herbal extracts packaged in polymers derived from natural substances can Continue Reading

Enzalutamide shows survival benefit in men with metastatic prostate cancer

A combination of enzalutamide and androgen deprivation therapy (ADT) significantly reduced the risk of metastatic progression or death over time in men with advanced prostate cancer, according to the results of clinical trial led by Duke Cancer Institute. The findings, published in the Journal of Clinical Oncology, were the product Continue Reading

Study shows stimulation of the ear can help manage Parkinson’s symptoms

A new study led by the University has shown that gentle, controlled stimulation of the ear canal can help reduce symptoms of Parkinson’s disease. The randomized, controlled study showed that twice-daily stimulation for two months was associated with a significant reduction in both motor and non-motor features of Parkinson’s disease. Continue Reading