Could microorganisms in poop help treat the deadliest form of skin cancer?

A multidisciplinary team at Lawson Health Research Institute is exploring whether fecal transplants can improve outcomes in melanoma patients treated with immunotherapy. Immunotherapy drugs stimulate a person’s immune system to attack and destroy cancer. While they can significantly improve survival outcomes in those with melanoma, they are only effective in Continue Reading

Using math to help treat Alzheimer’s, Parkinson’s and other diseases

Protein aggregation—in which misfolded proteins clump together to form large fibrils—has been implicated in many diseases including Alzheimer’s, Parkinson’s, and type II diabetes. While the exact role these fibrils play in diseases isn’t fully understood, many of the current treatments for diseases like Alzheimer’s and Parkinson’s target the aggregation process. Continue Reading

Study: Naltrexone to treat opioid use disorder during pregnancy, favorable for mom, baby

BOSTON -Infants born to mothers taking naltrexone to treat opioid use disorder during pregnancy developed no signs of neonatal opioid withdrawal syndrome (NOWS) during their hospitalization, a new study shows. In comparison to infants of mothers taking buprenorphine during pregnancy, infants exposed to naltrexone had shorter hospital stays, and mothers Continue Reading

High-energy lasers could be used to treat Alzheimer’s disease in the future

Amyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are known to be a cause of several diseases—including Alzheimer’s—and therefore, it is of immense scientific interest to understand how these aggregates can be broken. Some types of amyloid fibrils also play Continue Reading

Drug approved to treat tenosynovial giant cell tumor

(HealthDay)—Turalio (pexidartinib) capsules have been approved to treat adults with symptomatic tenosynovial giant cell tumor (TGCT), the U.S. Food and Drug Administration announced. The drug was approved for patients with TGCT with severe morbidity or functional limitations that has not improved with surgery. Turalio is only available through the Risk Continue Reading

Researchers discover therapy to treat drug-resistant acute lymphoblastic leukemia

Acute lymphoblastic leukemia accounts for one in five adult leukemias, and is the most common pediatric cancer in the United States. While new immune therapies have helped improve survival rates, some patients are unresponsive to existing treatment regimens. In addition, drug-related toxicities and drug resistance are rampant for these patients, Continue Reading

Medications used to treat atrial fibrillation may raise risk of falls

For older adults, fainting and falls are serious health concerns. They can lead to injury, hospitalization, and other severe consequences. Having certain chronic conditions, as well as taking certain medications, can raise your risk of experiencing falls and fall-related injuries. One condition that contributes to fainting and falls is atrial Continue Reading

Understanding what causes brain fog and how to treat it

The scientific community defined cognitive dysfunction, more commonly known as brain fog, as a mental condition characterized by bouts of confusion or reduced levels of clarity. The disorder was known to affect both men and women across all age groups. In fact, data from the U.S. Preventive Services Task Force (USPSTF) showed that between three percent and 42 percent of Continue Reading