Study identifies brain protein that could put the brakes on Alzheimer’s

University of California, Irvine biologists blazing new approaches to studying Alzheimer’s disease have made a major finding on combating inflammation linked to the disease. The School of Biological Sciences researchers’ discovery about the role of a protein called TOM-1 heralds a shift toward examining the molecular underpinnings of Alzheimer’s processes. Continue Reading

Common nutrient supplementation may hold the answers to combatting Alzheimer’s disease

In a new study, Biodesign researchers reveal that a lifelong dietary regimen of choline holds the potential to prevent Alzheimer’s disease (AD). Choline is a safe and easy-to-administer nutrient that is naturally present in some foods and can be used as a dietary supplement. Lead author Ramon Velazquez and his Continue Reading

Tracking Alzheimer’s disease pathology in single neuronal cells

University of Warwick researchers have developed a superior method to describe the very earliest effects that Alzheimer’s Disease proteins have on the properties of brain cells. In the paper “Introduction of Tau oligomers into cortical neurons alters action potential dynamics and disrupts synaptic transmission and plasticity,” published in the journal Continue Reading

Yo-yoing blood pressure could be bad for those with Alzheimer’s

Fluctuating blood pressure may be associated with worsening dementia in people with Alzheimer’s disease, according to new research. The study published Monday in the American Heart Association journal Hypertension sought to add a new understanding about the links between Alzheimer’s, the heart and blood vessels. Past research shows blood pressure Continue Reading

Exercise may slow brain deterioration in Alzheimer disease

(HealthDay)—Exercising may delay brain deterioration in people at high risk for Alzheimer disease, according to a proof-of-concept study published Sept. 17 in the Journal of Alzheimer’s Disease. Takashi Tarumi, Ph.D., from Texas Health Presbyterian Hospital in Dallas, and colleagues randomly assigned 70 patients with amnestic mild cognitive impairment (aMCI) to Continue Reading

Alzheimer’s study: Electrostimulation to evoke vivid memories

Alzheimer’s disease is one of the most dreaded diagnoses, and the fear is particularly acute among older people. This complex brain disorder, which usually affects older individuals, can cause many cognitive disabilities, most notably memory impairment. About 5.7 million Americans are living with Alzheimer’s disease. In addition, millions of loved Continue Reading

Alzheimer’s memory loss reversed by new head device using electromagnetic waves

There is finally some encouraging news for the millions of Americans suffering from Alzheimer’s Disease. NeuroEM Therapeutics today announced findings from an open label clinical trial showing reversal of cognitive impairment in Alzheimer’s Disease patients after just two months of treatment using the company’s wearable head device for in-home treatment. Continue Reading

Alzheimer’s breakthrough: Two short strings of amino acids could pave the way to new treatments

Two years after discovering a way to neutralize a rogue protein linked to Alzheimer’s disease, University of Alberta Distinguished University Professor and neurologist Jack Jhamandas has found a new piece of the Alzheimer’s puzzle, bringing him closer to a treatment for the disease. In a study published in Scientific Reports, Continue Reading

Researchers have identified areas of the retina that change in mild Alzheimer’s disease

Researchers at the Complutense University of Madrid (UCM) have identified changes in retinal layer thickness, inflammation or thinning in patients with mild Alzheimer’s disease, confirming that the retina is one of the most important biomarkers for early diagnosis of the disease. For the first time, researchers have determined the shape Continue Reading

New drug may protect against memory loss in Alzheimer’s disease

A new drug discovered through a research collaboration between the University at Buffalo and Tetra Therapeutics may protect against memory loss, nerve damage and other symptoms of Alzheimer’s disease. Preclinical research found that the drug—called BPN14770—deters the effects of amyloid beta, a hallmark protein of Alzheimer’s that is toxic to Continue Reading

Progress in understanding Alzheimer’s disease genetics, hope remains for drugs in testing

What is happening with Alzheimer’s disease research and treatment? We heard from Maria Carrillo, chief science officer of the nationwide Alzheimer’s Association, during a recent visit to San Diego. Here are some questions and answers from the interview, edited for space and clarity. Q: There have been several failed clinical Continue Reading

Alzheimer’s research increasingly focused on links to sleep and other behaviors

Sleep and other behavioral topics are growing within Alzheimer’s disease research, according to a new report released today by Elsevier, a global information analytics business specializing in science and health. To coincide with World Alzheimer’s Month, Elsevier analyzed Alzheimer’s research published since the 1970s offering a comprehensive view of the Continue Reading

Creation of new brain cells plays an underappreciated role in Alzheimer’s disease

Much of the research on the underlying causes of Alzheimer’s disease focuses on amyloid beta (Aß), a protein that accumulates in the brain as the disease progresses. Excess Aß proteins form clumps or “plaques” that disrupt communication between brain cells and trigger inflammation, eventually leading to widespread loss of neurons Continue Reading

Carriers of Alzheimer’s genetic marker have greater difficulty harnessing past knowledge

Adults carrying a gene associated with a higher risk of Alzheimer’s disease had a harder time accessing recently acquired knowledge, even though they didn’t show any symptoms of memory problems, according to findings published in a joint Baycrest-University of Oxford study. Researchers found that older adults carrying a specific strain Continue Reading