Researchers discover a new way that telomerase acts to keep cancer cells multiplying

Faster cancer treatments may be possible thanks to research from Children’s Medical Research Institute (CMRI). Researchers were surprised to discover a new way that an enzyme in cancer cells, telomerase, acts to keep cancer cells multiplying. This could mean a faster way to stop cancer cells in their tracks. Tracy Continue Reading

Researchers discover new, treatable pathway known to cause hypertension in obese people

There’s no question that as body weight increases, so too does blood pressure. Now, in a study of mice, Johns Hopkins researchers have revealed exactly which molecules are likely responsible for the link between obesity and blood pressure. Blocking one of these molecules—a signaling channel that’s found in a tiny Continue Reading

100-year-old scientific mystery solved: Researchers discover role of nuclear glycogen in non-small cell lung cancers

Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung cancers. Published in Cell Metabolism, the research centers on the function of glycogen Continue Reading

Scientists discover a direct link from the brain’s emotion circuit to the movement circuit

During high stress situations such as making a goal in soccer, some athletes experience a rapid decline in performance under pressure, known as “choking.” Now, Salk Institute researchers have uncovered what might be behind the phenomenon: one-way signals from the brain’s emotion circuit to the movement circuit. The study, which Continue Reading

Scientists discover hidden differences among cells that may help them evade drug therapy

University of Maryland researchers have discovered that seemingly identical cells can use different protein molecules to carry out the same function in an important cellular process. The scientists named this newly discovered variability “functional mosaicism,” and it has significant implications for the development of therapeutic treatments, which are often designed Continue Reading

Researchers discover a new mechanism that could counteract obesity

Obesity rates worldwide have nearly tripled since 1975. Now, new research from the University of Minnesota Medical School has discovered, in rodents, critical mutations in molecules implicated in obesity, which may help inform the development of new anti-obesity therapies. Lead author Alessandro Bartolomucci, Ph.D., Associate Professor in the Department of Continue Reading

Biophysicists discover how ‘Australian’ mutation leads to Alzheimer’s disease

A team of scientists from the Moscow Institute of Physics and Technology (MIPT) and Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (IBCh RAS) studied one hereditary genetic mutation to discover general molecular mechanisms that may lead both to early onset of Alzheimer’s disease and to the form of the disease caused by Continue Reading

Researchers discover that fasting reduces inflammation and improves chronic inflammatory diseases

Fasting regimens have gained public and scientific interest in recent years, but fasting shouldn’t be dismissed as a fad. In a study published in Cell, Mount Sinai researchers found that fasting reduces inflammation and improves chronic inflammatory diseases without affecting the immune system’s response to acute infections. While acute inflammation Continue Reading

Researchers discover blocking key mineral uptake could prevent gonorrhea infection

Blocking the ability of the bacterial pathogen that causes gonorrhea to uptake the mineral zinc can stop infection by this widespread sexually transmitted infection, according to a study by the Institute for Biomedical Sciences at Georgia State University. The findings, published in the journal PLoS Pathogens, could be used to Continue Reading