Researchers identify metabolic cycles in baby teeth linked to ADHD and autism in children

Mount Sinai researchers have identified elemental signatures in baby teeth that are unique to attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, and cases when both neurodevelopment conditions are present, which suggests that the metabolic regulation of nutrients and toxins play a role in these diseases, according to a study published in Continue Reading

Resistance to immune checkpoint blocker drug linked to metabolic imbalance

A metabolic imbalance in some cancer patients following treatment with a checkpoint inhibitor drug, nivolumab, is associated with resistance to the immunotherapy agent and shorter survival, report scientists from Dana-Farber Cancer Institute, in collaborative work with the Broad Institute of MIT and Harvard. The chemical change, which the investigators say Continue Reading

‘Metabolic inhibitor’ compound extends survival in mice with MYC-expressing pediatric brain tumors

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results Continue Reading

Metabolic reprogramming of branched-chain amino acid facilitates drug resistance in lung cancer

Despite the remarkable success of molecular targeted therapy in recent years, the rapid increase of drug resistance is a major obstacle to effective treatment of lung cancer. How do lung cancer cells adapt to targeted therapy? What is the molecular basis of such adaptive behavior? Can this adaptive response be Continue Reading

Metabolic reprogramming of branched-chain amino acid facilitates drug resistance in lung cancer

Credit: CC0 Public Domain Despite the remarkable success of molecular targeted therapy in recent years, the rapid increase of drug resistance is a major obstacle to effective treatment of lung cancer. How do lung cancer cells adapt to targeted therapy? What is the molecular basis of such adaptive behavior? Can Continue Reading

Managing metabolic syndrome with integrated naturopathy and yoga

During the course of treatment for a 50-year-old male patient with metabolic syndrome, a case study determined that Integrated Yoga and Naturopathy (IYN) showed promise in the management of metabolic syndrome (MetS). The researchers registered reduction in parameters associated with the patient’s cluster of medical conditions. The case study was published in the Journal of Continue Reading

Polyphenols in dark chocolate protect against metabolic syndrome

Consumption of dark chocolate has been associated with the reduction in several markers of cardiometabolic risk. The following study, which was published in the Journal of Nutrition & Intermediary Metabolism, aimed to examine the association of dark chocolate consumption with levels of anxiety, particularly the presence of metabolic syndrome (MetS). During 2001-2002, the Continue Reading

Genetically engineered “golden rice” suffers “metabolic meltdown” and devastating yield plunge as GE technology goes horribly wrong

Supporters of genetically modified organisms (GMOs) have long claimed that Golden Rice is key in alleviating vitamin A deficiency, but it turns out that’s not at all the case. According to a new report by Indian researchers, the genes necessary to produce Golden Rice cause unintended side effects, Independent Science Continue Reading

Experts warn there is a new variant to metabolic problems: Type 3c diabetes is being misdiagnosed, which is why many aren’t responding to treatment

Misdiagnosing another form of diabetes, called type 3c diabetes or pancreatogenic diabetes, as type 2 diabetes, is making patients sicker by undergoing the wrong treatment plan, a study published in Diabetes Care has warned. According to experts, various markers – such as pancreatic inflammation, abnormal pancreatic tissue growth or surgical removal of all or certain parts of Continue Reading