Researchers discover a new way that telomerase acts to keep cancer cells multiplying

Faster cancer treatments may be possible thanks to research from Children’s Medical Research Institute (CMRI). Researchers were surprised to discover a new way that an enzyme in cancer cells, telomerase, acts to keep cancer cells multiplying. This could mean a faster way to stop cancer cells in their tracks. Tracy Continue Reading

Genetics researchers find new neurodevelopmental syndrome

Researchers have identified a gene mutation that causes developmental delay, intellectual disability, behavioral abnormalities and musculoskeletal problems in children. The newly diagnosed condition, called NKAP-related syndrome, arises from mutations in the NKAP gene, which plays a key role in human development. “This gene mutation disrupts transcription, the process in which Continue Reading

Researchers create new viral vector for improved gene therapy in sickle cell disease

Researchers at the National Institutes of Health have developed a new and improved viral vector—a virus-based vehicle that delivers therapeutic genes—for use in gene therapy for sickle cell disease. In advanced lab tests using animal models, the new vector was up to 10 times more efficient at incorporating corrective genes Continue Reading

Researchers identify molecular process that could accelerate recovery from nerve injuries

Twenty million Americans suffer from peripheral nerve injuries, which can be caused by traumas such as combat wounds and motorcycle crashes as well as medical disorders including diabetes. These injuries can have a devastating impact on quality of life, resulting in loss of sensation, motor function and long-lasting nerve pain. Continue Reading

Researchers publish comprehensive review on respiratory effects of vaping

Four scientists from four leading universities in the United States conducted a comprehensive review of all e-cigarette/vaping peer-reviewed scientific papers that pertain to the lungs and published their findings today in the British Medical Journal. Corresponding author Rob Tarran, Ph.D., professor of cell biology and physiology and member of the Continue Reading

Researchers advance search for safer, easier way to deliver vision-saving gene therapy

In experiments with rats, pigs and monkeys, Johns Hopkins Medicine researchers have developed a way to deliver sight-saving gene therapy to the retina. If proved safe and effective in humans, the technique could provide a new, more permanent therapeutic option for patients with common diseases such as wet age-related macular Continue Reading

Researchers find shorter sleep periods associated with obesity in African Americans

Research in The Journal of the American Osteopathic Association found an association between sleep duration and obesity among African Americans. Although some populations are more susceptible to becoming overweight or obese, prior studies have not focused on minorities, the authors wrote. This study examined associations between the participants’ body mass Continue Reading

Researchers develop program aimed at reducing dating violence among students

A program developed to encourage healthy relationships and reduce dating violence was effective among early middle school students, according to results of a study published in the American Journal of Public Health by researchers at The University of Texas Health Science Center at Houston (UTHealth). The intervention program, named Me Continue Reading

Researchers examine causes, effects, treatments for alcohol use disorder

New research from Regents’ Professor Katie Witkiewitz at The University of New Mexico Department of Psychology and Center on Alcoholism, Substance Abuse, and Addictions examines alcohol use disorder, the physical and economic toll it takes, and effective treatments that are now available. Witkiewitz and her colleagues, Barbara McCrady (Distinguished Professor Continue Reading

Researchers uncover molecular changes associated with treating lymphatic filariasis

The Global Program to Eliminate Lymphatic Filariasis delivers mass drug administration to 500 million people each year, and adverse events are common following treatment. Now, researchers have reported in PLOS Neglected Tropical Diseases that certain changes in gene expression are associated with these adverse events. Lymphatic filariasis (LF) is a Continue Reading

Researchers identify metabolic cycles in baby teeth linked to ADHD and autism in children

Mount Sinai researchers have identified elemental signatures in baby teeth that are unique to attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, and cases when both neurodevelopment conditions are present, which suggests that the metabolic regulation of nutrients and toxins play a role in these diseases, according to a study published in Continue Reading

Researchers discover new, treatable pathway known to cause hypertension in obese people

There’s no question that as body weight increases, so too does blood pressure. Now, in a study of mice, Johns Hopkins researchers have revealed exactly which molecules are likely responsible for the link between obesity and blood pressure. Blocking one of these molecules—a signaling channel that’s found in a tiny Continue Reading