Scientists find potential diagnostic tool, treatment for Parkinson’s disease

Investigators at the Stanford University School of Medicine have pinpointed a molecular defect that seems almost universal among patients with Parkinson’s disease and those at a high risk of acquiring it. The discovery could provide a way of detecting the neurodegenerative disorder in its earliest stages, before symptoms start to Continue Reading

Scientists tackle potential drug resistance by using new single-cell genetic method

Using a new technique that can identify genetic profiles of individual cells, University of Notre Dame researchers modeled a breast cancer tumor’s potential resistance to a drug, and then identified a drug combination that reversed that resistance. Siyuan Zhang, the Dee Associate Professor of Biological Sciences at Notre Dame, and Continue Reading

Scientists identify a personality feature that could predict how often you exercise

Individuals who make concrete plans to meet their goals may engage in more physical activity, including visits to the gym, compared to those who don’t plan quite so far ahead, research shows. These research findings, published in Psychological Science, a journal of the Association for Psychological Science, suggest that self-reported Continue Reading

Scientists identify a possible new treatment for diabetic retinopathy

About one in three diabetic patients develops diabetic retinopathy (DR), which can impair vision and lead to blindness. A new study in The American Journal of Pathology, published by Elsevier, provides clear evidence that high glucose increases the levels of enzymatic precursor—lysyl oxidase propeptide (LOX-PP)—that promotes cell death, which was Continue Reading

Scientists develop new methodology to genetically modify lab mice and human cells

A team led by Cedars-Sinai has designed a rapid method to genetically alter laboratory mice and then used this method to produce personalized animal models of pediatric glioma, an aggressive type of malignant brain cancer in children. The new method overcomes several drawbacks in current techniques. The goal is to Continue Reading

Scientists project northward expansion of Valley fever by end of 21st century

Valley fever is endemic to hot and dry regions such as the southwestern United States and California’s San Joaquin Valley, but scientists at the University of California, Irvine predict that climate change will cause the fungal infection’s range to more than double in size this century, reaching previously unaffected areas Continue Reading

Scientists prove low cost arthritis drug can effectively treat blood cancer sufferers

A simple arthritis drug could be an effective, low cost solution to treat patients with blood cancers such as polycythemia vera (PV) and essential thrombocythemia (ET), a breakthrough study by the University of Sheffield has shown. Led by Dr. Martin Zeidler, from the University of Sheffield’s Department of Biomedical Science Continue Reading

Can scientists predict which cancer markers are likely to trigger an immune response?

Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have designed and validated a model for predicting what might make an effective cancer vaccine against a patient’s tumor. This finding could help overcome a significant obstacle in the development of personalized cancer vaccines. In a study published in Continue Reading